 ARGED BM SLAM STAL OSTRÓW WLKP. | VS |  ENEA ZASTAL BC ZIELONA GÓRA | 1 September 2021 20:00 | Wałbrzych | 69:84 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS |  ŚLĄSK WROCŁAW | 5 September 2021 20:30 | Zielona Góra | 81:71 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS |  MKS DĄBROWA GÓRNICZA | 8 September 2021 18:00 | Zielona Góra | 91:79 | |
 ANWIL WŁOCŁAWEK | VS | ENEA ZASTAL BC ZIELONA GÓRA | 11 September 2021 17:30 | Włocławek | 89:82 | |
 HYDROTRUCK RADOM | VS | ENEA ZASTAL BC ZIELONA GÓRA | 14 September 2021 17:30 | Radom | 89:92 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS |  STK CZARNI SŁUPSK | 17 September 2021 17:30 | Zielona Góra | 83:91 | |
 KING SZCZECIN | VS | ENEA ZASTAL BC ZIELONA GÓRA | 23 September 2021 17:30 | Szczecin | 86:96 | |
 CSKA | VS | ENEA ZASTAL BC ZIELONA GÓRA | 26 September 2021 14:00 | Moskwa | 105:71 | |
 UNICS | VS | ENEA ZASTAL BC ZIELONA GÓRA | 28 September 2021 18:00 | Kazań | 92:63 | |
 TREFL SOPOT | VS | ENEA ZASTAL BC ZIELONA GÓRA | 9 October 2021 17:30 | Sopot | 93:89 | |
 Astana | VS | ENEA ZASTAL BC ZIELONA GÓRA | 16 October 2021 10:00 | Nur-Sułtan | 84:70 | |
 TWARDE PIERNIKI TORUŃ | VS | ENEA ZASTAL BC ZIELONA GÓRA | 21 October 2021 19:30 | Toruń | 95:77 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS |  Nizhny Novgorod | 25 October 2021 18:00 | Zielona Góra | 77:95 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS |  GTK GLIWICE | 28 October 2021 17:30 | Zielona Góra | 102:82 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS |  Tsmoki-Minsk | 31 October 2021 15:00 | Zielona Góra | 96:64 | |
 PGE SPÓJNIA STARGARD | VS | ENEA ZASTAL BC ZIELONA GÓRA | 4 November 2021 17:30 | Stargard | 53:96 | |
 Zenit | VS | ENEA ZASTAL BC ZIELONA GÓRA | 8 November 2021 18:00 | Sankt Petersburg | 97:80 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS |  Lokomotiv-Kuban | 13 November 2021 19:00 | Zielona Góra | 90:98 | |
| ARGED BM SLAM STAL OSTRÓW WLKP. | VS | ENEA ZASTAL BC ZIELONA GÓRA | 16 November 2021 17:30 | Ostrów Wlkp. | 105:98 | |
 PSZCZÓŁKA START LUBLIN | VS | ENEA ZASTAL BC ZIELONA GÓRA | 19 November 2021 17:30 | Lublin | 73:99 | |
 ARKA GDYNIA | VS | ENEA ZASTAL BC ZIELONA GÓRA | 2 December 2021 19:30 | Gdynia | 73:83 | |
 PARMA | VS | ENEA ZASTAL BC ZIELONA GÓRA | 6 December 2021 15:00 | Perm | 83:72 | |
 Avtodor | VS | ENEA ZASTAL BC ZIELONA GÓRA | 11 December 2021 14:00 | Saratov | 81:74 | |
 ENEA ABRAMCZYK ASTORIA BYDGOSZCZ | VS | ENEA ZASTAL BC ZIELONA GÓRA | 16 December 2021 17:30 | Bydgoszcz | 106:88 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | CSKA | 20 December 2021 19:00 | Zielona Góra | 59:93 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS |  LEGIA WARSZAWA | 22 December 2021 18:00 | Zielona Góra | 100:66 | |
| ŚLĄSK WROCŁAW | VS | ENEA ZASTAL BC ZIELONA GÓRA | 27 December 2021 19:00 | Wrocław | 85:88 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | ANWIL WŁOCŁAWEK | 2 January 2022 17:30 | Zielona Góra | 79:83 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | KING SZCZECIN | 12 January 2022 18:00 | Zielona Góra | 87:71 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | PSZCZÓŁKA START LUBLIN | 20 January 2022 17:30 | Zielona Góra | 85:70 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | UNICS | 23 January 2022 19:00 | Zielona Góra | 80:85 | |
| MKS DĄBROWA GÓRNICZA | VS | ENEA ZASTAL BC ZIELONA GÓRA | 28 January 2022 20:00 | Dąbrowa Górnicza | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | Astana | 31 January 2022 18:00 | Zielona Góra | ||
| LEGIA WARSZAWA | VS | ENEA ZASTAL BC ZIELONA GÓRA | 5 Febryary 2022 00:00 | Warszawa | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | TWARDE PIERNIKI TORUŃ | 9 Febryary 2022 00:00 | Zielona Góra | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | Zenit | 14 Febryary 2022 19:00 | Zielona Góra | ||
| GTK GLIWICE | VS | ENEA ZASTAL BC ZIELONA GÓRA | 3 March 2022 00:00 | Gliwice | ||
| Nizhny Novgorod | VS | ENEA ZASTAL BC ZIELONA GÓRA | 6 March 2022 00:00 | Nizhny Novgorod | ||
| STK CZARNI SŁUPSK | VS | ENEA ZASTAL BC ZIELONA GÓRA | 10 March 2022 00:00 | Słupsk | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS |  Enisey | 14 March 2022 00:00 | Zielona Góra | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | HYDROTRUCK RADOM | 17 March 2022 00:00 | Zielona Góra | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | PARMA | 20 March 2022 00:00 | Zielona Góra | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | TREFL SOPOT | 23 March 2022 00:00 | Zielona Góra | ||
| Tsmoki-Minsk | VS | ENEA ZASTAL BC ZIELONA GÓRA | 26 March 2022 00:00 | Mińsk | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | ARKA GDYNIA | 31 March 2022 00:00 | Zielona Góra | ||
| Lokomotiv-Kuban | VS | ENEA ZASTAL BC ZIELONA GÓRA | 3 April 2022 00:00 | Krasnodar | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | ARGED BM SLAM STAL OSTRÓW WLKP. | 6 April 2022 00:00 | Zielona Góra | ||
 Kalev | VS | ENEA ZASTAL BC ZIELONA GÓRA | 10 April 2022 00:00 | Tallinn | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | ENEA ABRAMCZYK ASTORIA BYDGOSZCZ | 13 April 2022 00:00 | Zielona Góra | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | Avtodor | 16 April 2022 00:00 | Zielona Góra |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | ŚLĄSK WROCŁAW | 5 September 2021 20:30 | Zielona Góra | 81:71 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | MKS DĄBROWA GÓRNICZA | 8 September 2021 18:00 | Zielona Góra | 91:79 | |
| ANWIL WŁOCŁAWEK | VS | ENEA ZASTAL BC ZIELONA GÓRA | 11 September 2021 17:30 | Włocławek | 89:82 | |
| HYDROTRUCK RADOM | VS | ENEA ZASTAL BC ZIELONA GÓRA | 14 September 2021 17:30 | Radom | 89:92 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | STK CZARNI SŁUPSK | 17 September 2021 17:30 | Zielona Góra | 83:91 | |
| KING SZCZECIN | VS | ENEA ZASTAL BC ZIELONA GÓRA | 23 September 2021 17:30 | Szczecin | 86:96 | |
| TREFL SOPOT | VS | ENEA ZASTAL BC ZIELONA GÓRA | 9 October 2021 17:30 | Sopot | 93:89 | |
| TWARDE PIERNIKI TORUŃ | VS | ENEA ZASTAL BC ZIELONA GÓRA | 21 October 2021 19:30 | Toruń | 95:77 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | GTK GLIWICE | 28 October 2021 17:30 | Zielona Góra | 102:82 | |
| PGE SPÓJNIA STARGARD | VS | ENEA ZASTAL BC ZIELONA GÓRA | 4 November 2021 17:30 | Stargard | 53:96 | |
| ARGED BM SLAM STAL OSTRÓW WLKP. | VS | ENEA ZASTAL BC ZIELONA GÓRA | 16 November 2021 17:30 | Ostrów Wlkp. | 105:98 | |
| PSZCZÓŁKA START LUBLIN | VS | ENEA ZASTAL BC ZIELONA GÓRA | 19 November 2021 17:30 | Lublin | 73:99 | |
| ARKA GDYNIA | VS | ENEA ZASTAL BC ZIELONA GÓRA | 2 December 2021 19:30 | Gdynia | 73:83 | |
| ENEA ABRAMCZYK ASTORIA BYDGOSZCZ | VS | ENEA ZASTAL BC ZIELONA GÓRA | 16 December 2021 17:30 | Bydgoszcz | 106:88 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | LEGIA WARSZAWA | 22 December 2021 18:00 | Zielona Góra | 100:66 | |
| ŚLĄSK WROCŁAW | VS | ENEA ZASTAL BC ZIELONA GÓRA | 27 December 2021 19:00 | Wrocław | 85:88 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | ANWIL WŁOCŁAWEK | 2 January 2022 17:30 | Zielona Góra | 79:83 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | KING SZCZECIN | 12 January 2022 18:00 | Zielona Góra | 87:71 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | PSZCZÓŁKA START LUBLIN | 20 January 2022 17:30 | Zielona Góra | 85:70 | |
| MKS DĄBROWA GÓRNICZA | VS | ENEA ZASTAL BC ZIELONA GÓRA | 28 January 2022 20:00 | Dąbrowa Górnicza | ||
| LEGIA WARSZAWA | VS | ENEA ZASTAL BC ZIELONA GÓRA | 5 Febryary 2022 00:00 | Warszawa | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | TWARDE PIERNIKI TORUŃ | 9 Febryary 2022 00:00 | Zielona Góra | ||
| GTK GLIWICE | VS | ENEA ZASTAL BC ZIELONA GÓRA | 3 March 2022 00:00 | Gliwice | ||
| STK CZARNI SŁUPSK | VS | ENEA ZASTAL BC ZIELONA GÓRA | 10 March 2022 00:00 | Słupsk | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | HYDROTRUCK RADOM | 17 March 2022 00:00 | Zielona Góra | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | TREFL SOPOT | 23 March 2022 00:00 | Zielona Góra | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | ARKA GDYNIA | 31 March 2022 00:00 | Zielona Góra | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | ARGED BM SLAM STAL OSTRÓW WLKP. | 6 April 2022 00:00 | Zielona Góra | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | ENEA ABRAMCZYK ASTORIA BYDGOSZCZ | 13 April 2022 00:00 | Zielona Góra |
| CSKA | VS | ENEA ZASTAL BC ZIELONA GÓRA | 26 September 2021 14:00 | Moskwa | 105:71 | |
| UNICS | VS | ENEA ZASTAL BC ZIELONA GÓRA | 28 September 2021 18:00 | Kazań | 92:63 | |
| Astana | VS | ENEA ZASTAL BC ZIELONA GÓRA | 16 October 2021 10:00 | Nur-Sułtan | 84:70 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | Nizhny Novgorod | 25 October 2021 18:00 | Zielona Góra | 77:95 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | Tsmoki-Minsk | 31 October 2021 15:00 | Zielona Góra | 96:64 | |
| Zenit | VS | ENEA ZASTAL BC ZIELONA GÓRA | 8 November 2021 18:00 | Sankt Petersburg | 97:80 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | Lokomotiv-Kuban | 13 November 2021 19:00 | Zielona Góra | 90:98 | |
| PARMA | VS | ENEA ZASTAL BC ZIELONA GÓRA | 6 December 2021 15:00 | Perm | 83:72 | |
| Avtodor | VS | ENEA ZASTAL BC ZIELONA GÓRA | 11 December 2021 14:00 | Saratov | 81:74 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | CSKA | 20 December 2021 19:00 | Zielona Góra | 59:93 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | UNICS | 23 January 2022 19:00 | Zielona Góra | 80:85 | |
| ENEA ZASTAL BC ZIELONA GÓRA | VS | Astana | 31 January 2022 18:00 | Zielona Góra | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | Zenit | 14 Febryary 2022 19:00 | Zielona Góra | ||
| Nizhny Novgorod | VS | ENEA ZASTAL BC ZIELONA GÓRA | 6 March 2022 00:00 | Nizhny Novgorod | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | Enisey | 14 March 2022 00:00 | Zielona Góra | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | PARMA | 20 March 2022 00:00 | Zielona Góra | ||
| Tsmoki-Minsk | VS | ENEA ZASTAL BC ZIELONA GÓRA | 26 March 2022 00:00 | Mińsk | ||
| Lokomotiv-Kuban | VS | ENEA ZASTAL BC ZIELONA GÓRA | 3 April 2022 00:00 | Krasnodar | ||
| Kalev | VS | ENEA ZASTAL BC ZIELONA GÓRA | 10 April 2022 00:00 | Tallinn | ||
| ENEA ZASTAL BC ZIELONA GÓRA | VS | Avtodor | 16 April 2022 00:00 | Zielona Góra |
| ARGED BM SLAM STAL OSTRÓW WLKP. | VS | ENEA ZASTAL BC ZIELONA GÓRA | 1 September 2021 20:00 | Wałbrzych | 69:84 |